An Overview, Dermatological Uses, Side effects and Risk factors

Family: Apocynaceae
Latin name: Wrightia tinctoria
English name: Pala Indigo
Hindi name: Mitaindrajau
Taste: Bitter, Astringent
Nature: Cold
Parts used: Leaves, Bark, Seeds
Description:
It is a deciduous flowering plant that grows up to 25 M. It grows in a temperate climate.

Phytochemical constituents:
Beta Sitosterol, Beta Amyrin, Cycloartenone

Mode of action: Kapha Pitta shamak

• Impairs keratinocytes multiplication
• Interferes in co-stimulatory molecules communications
• Sorts, isolates and attenuates neoplastic KC
• Antibacterial (E.coli, B. subtilis, S. aureus)
• Antiulcer, Antiinflammatory, Wound healing
• Carminative, Anthelmintic
• Astringent, Depurative
• Antipyretic

Therapeutic Benefits: 
Secondary

• Psoriasis
• Reduces xerosis of skin and associated itching
• Delays cell death and prolongs cell cycle turn over time
• Prolongs period of remission in Ps
• High Blood Pressure
• Diarrhoea

Tertiary

• Toothache
• Ringworm
• Leprosy​

Side effects and Risk factors:

1. LIKELY SAFE for most people when applied topically.
2. Side effects have not been documented, so Avoid orally In Pregnancy and Breast feeding.

​        – Dr Malika Ahuja